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1

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

Huntzinger, Eric, Izaurralde, Elisa

Journal:

Nature Reviews Genetics

Year:

2011

Language:

english

File:

PDF, 799 KB

english, 2011

2

P bodies: at the crossroads of post-transcriptional pathways

Eulalio, Ana, Behm-Ansmant, Isabelle, Izaurralde, Elisa

Journal:

Nature Reviews Molecular Cell Biology

Year:

2007

Language:

english

File:

PDF, 556 KB

english, 2007

3

Nucleus and gene expression: The interplay of transcriptional and post-transcriptional mechanisms that regulate gene expression

Elisa Izaurralde, David L Spector

Journal:

Current Opinion in Cell Biology

Year:

2004

Language:

english

File:

PDF, 69 KB

english, 2004

4

Structure and dynamics of the post-transcriptional mRNA-processing machinery

Elisa Izaurralde

Journal:

Year:

2000

Language:

english

File:

PDF, 936 KB

english, 2000

5

Towards a molecular understanding of microRNA-mediated gene silencing

Jonas, Stefanie, Izaurralde, Elisa

Journal:

Nature Reviews Genetics

Year:

2015

Language:

english

File:

PDF, 5.46 MB

english, 2015

6

A cap-binding protein complex mediating U snRNA export

Izaurralde, Elisa, Lewis, Joe, Gamberi, Chiara, Jarmolowski, Artur, McGuigan, Caroline, Mattaj, Iain W.

Journal:

Year:

1995

File:

PDF, 1.29 MB

1995

7

The C-terminal α–α superhelix of Pat is required for mRNA decapping in metazoa

Braun, Joerg E, Tritschler, Felix, Haas, Gabrielle, Igreja, Cátia, Truffault, Vincent, Weichenrieder, Oliver, Izaurralde, Elisa

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

8

Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing

Huntzinger, Eric, Braun, Joerg E, Heimstädt, Susanne, Zekri, Latifa, Izaurralde, Elisa

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

9

Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein

Boland, Andreas, Tritschler, Felix, Heimstädt, Susanne, Izaurralde, Elisa, Weichenrieder, Oliver

Journal:

Year:

2010

Language:

english

File:

PDF, 869 KB

english, 2010

10

Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

Lingel, Andreas, Simon, Bernd, Izaurralde, Elisa, Sattler, Michael

Journal:

Year:

2003

Language:

english

File:

PDF, 358 KB

english, 2003

11

An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay

Palacios, Isabel M., Gatfield, David, St Johnston, Daniel, Izaurralde, Elisa

Journal:

Year:

2004

Language:

english

File:

PDF, 377 KB

english, 2004

12

Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila

Gatfield, David, Izaurralde, Elisa

Journal:

Year:

2004

Language:

english

File:

PDF, 331 KB

english, 2004

13

An efficient protein complex purification method for functional proteomics in higher eukaryotes

Forler, Daniel, Köcher, Thomas, Rode, Michaela, Gentzel, Mark, Izaurralde, Elisa, Wilm, Matthias

Journal:

Nature Biotechnology

Year:

2002

Language:

english

File:

PDF, 1.32 MB

english, 2002

14

Freedom versus constraint in protein function

Izaurralde, Elisa

Journal:

Nature Reviews Molecular Cell Biology

Year:

2009

Language:

english

File:

PDF, 138 KB

english, 2009

15

Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu

Tritschler, Felix, Huntzinger, Eric, Izaurralde, Elisa

Journal:

Nature Reviews Molecular Cell Biology

Year:

2010

Language:

english

File:

PDF, 457 KB

english, 2010

16

A novel mode of RBD-protein recognition in the Y14–Mago complex

Fribourg, Sébastien, Gatfield, David, Izaurralde, Elisa, Conti, Elena

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 1.40 MB

english, 2003

17

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

Eulalio, Ana, Huntzinger, Eric, Izaurralde, Elisa

Journal:

Nature Structural and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 464 KB

english, 2008

18

Directing mRNA export

Izaurralde, Elisa

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 268 KB

english, 2004

19

The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

Kadlec, Jan, Izaurralde, Elisa, Cusack, Stephen

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.15 MB

english, 2004

20

Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster

Rehwinkel, Jan, Herold, Andrea, Gari, Kerstin, Köcher, Thomas, Rode, Michaela, Ciccarelli, Francesca L, Wilm, Matthias, Izaurralde, Elisa

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.48 MB

english, 2004

21

Nucleic acid 3′-end recognition by the Argonaute2 PAZ domain

Simon, Bernd, Izaurralde, Elisa, Sattler, Michael, Lingel, Andreas

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 445 KB

english, 2004

22

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin α

Jínek, Martin, Rehwinkel, Jan, Lazarus, Brooke D, Izaurralde, Elisa, Hanover, John A, Conti, Elena

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.49 MB

english, 2004

23

Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex

Glavan, Filip, Behm-Ansmant, Isabelle, Izaurralde, Elisa, Conti, Elena

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 488 KB

english, 2006

24

A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay

Behm-Ansmant, Isabelle, Gatfield, David, Rehwinkel, Jan, Hilgers, Valérie, Izaurralde, Elisa

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

25

Molecular insights into the interaction of PYM with the Mago–Y14 core of the exon junction complex

Bono, Fulvia, Ebert, Judith, Unterholzner, Leonie, Güttler, Thomas, Izaurralde, Elisa, Conti, Elena

Journal:

Year:

2004

Language:

english

File:

PDF, 310 KB

english, 2004

26

The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition

Lingel, Andreas, Simon, Bernd, Izaurralde, Elisa, Sattler, Michael

Journal:

Year:

2005

Language:

english

File:

PDF, 303 KB

english, 2005

27

Delving into the diversity of silencing pathways. Symposium on MicroRNAs and siRNAs: Biological Functions and Mechanisms

Dorner, Silke, Eulalio, Ana, Huntzinger, Eric, Izaurralde, Elisa

Journal:

Year:

2007

Language:

english

File:

PDF, 428 KB

english, 2007

28

Letter to the Editor: NMR Assignment of theDrosophilaArgonaute2 PAZ Domain

Andreas Lingel, Bernd Simon, Elisa Izaurralde, Michael Sattler

Journal:

Journal of Biomolecular NMR

Year:

2004

Language:

english

File:

PDF, 67 KB

english, 2004

29

Prediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporins

Suyama, Mikita, Doerks, Tobias, Braun, Isabelle C., Sattler, Michael, Izaurralde, Elisa, Bork, Peer

Journal:

Year:

2000

Language:

english

File:

PDF, 1.12 MB

english, 2000

30

Transport of RNA between nucleus and cytoplasm

Elisa Izaurralde, Iain W. Mattaj

Journal:

Seminars in Cell Biology

Year:

1992

Language:

english

File:

PDF, 1.16 MB

english, 1992

31

Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

Elena Conti, Elisa Izaurralde

Journal:

Current Opinion in Cell Biology

Year:

2005

Language:

english

File:

PDF, 307 KB

english, 2005

32

Nucleus and gene expression

Elisa Izaurralde, Phillip D Zamore

Journal:

Current Opinion in Cell Biology

Year:

2009

Language:

english

File:

PDF, 94 KB

english, 2009

33

Nonsense-mediated mRNA decay: target genes and functional diversification of effectors

Jan Rehwinkel, Jeroen Raes, Elisa Izaurralde

Journal:

Trends in Biochemical Sciences

Year:

2006

Language:

english

File:

PDF, 518 KB

english, 2006

34

Nucleocytoplasmic transport enters the atomic age

Elena Conti, Elisa Izaurralde

Journal:

Current Opinion in Cell Biology

Year:

2001

Language:

english

File:

PDF, 301 KB

english, 2001

35

Cell biology: Paper alert

Arshad Desai, Elizabeth A Holleran, Serge Roche, Giulio Superti-Furga, Rein Aasland, Robert OJ Weinzierl, Elisa Izaurralde, Karl Matter, Paul A Slesinger, Martin Pfaff, Eric A Miska, Laurent Kodjabach

Journal:

Current Opinion in Cell Biology

Year:

1999

Language:

english

File:

PDF, 113 KB

english, 1999

36

Cell biology: Paper alert

Arshad Desai, Elizabeth A Holleran, Serge Roche, Rein Aasland, Robert OJ Weinzierl, Elisa Izaurralde, Karl Matter, Paul A Slesinger, Martin Pfaff, Neil Huckriede, Robert A Sclafani

Journal:

Current Opinion in Cell Biology

Year:

1999

Language:

english

File:

PDF, 110 KB

english, 1999

37

Cell biology

Clare M Waterman-Storer, Serge Roche, Giulio Superti-Furga, Rein Aasland, Robert OJ Weinzierl, Elisa Izaurralde, Karl Matter, Paul A Slesinger, Martin Pfaff, Eric A Miska, Reiko Toyama, Reiko Toyama,

Journal:

Current Opinion in Cell Biology

Year:

1999

Language:

english

File:

PDF, 118 KB

english, 1999

38

Cell biology: Paper alert

Julie Canman, Clare M Waterman-Storer, Serge Roche, Giulio Superti-Furga, Elisa Izaurralde, Rein Aasland, Peter Verrijzer, Karl Matter, Paul A Slesinger, Martin Pfaff, Eric A Miska, Robert A Sclafani

Journal:

Current Opinion in Cell Biology

Year:

1999

Language:

english

File:

PDF, 102 KB

english, 1999

39

NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation

Lin Jun, Suzanna Frints, Hein Duhamel, Andrea Herold, Jose Abad-Rodrigues, Carlos Dotti, Elisa Izaurralde, Peter Marynen, Guy Froyen

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 642 KB

english, 2001

40

The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila

David Gatfield, Hervé Le Hir, Christel Schmitt, Isabelle C Braun, Thomas Köcher, Matthias Wilm, Elisa Izaurralde

Journal:

Current Biology

Year:

2001

Language:

english

File:

PDF, 250 KB

english, 2001

41

The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export

Claudio Saavedra, Barbara Felber, Elisa Izaurralde

Journal:

Current Biology

Year:

1997

Language:

english

File:

PDF, 590 KB

english, 1997

42

The interplay of nuclear mRNP assembly, mRNA surveillance and export

Françoise Stutz, Elisa Izaurralde

Journal:

Trends in Cell Biology

Year:

2003

Language:

english

File:

PDF, 1015 KB

english, 2003

43

An immersion in nucleocytoplasmic transport at the Garda lake

Isabel Palacios, Elisa Izaurralde

Journal:

Trends in Cell Biology

Year:

1997

Language:

english

File:

PDF, 404 KB

english, 1997

44

A novel family of nuclear transport receptors mediates the export of messenger RNA to the cytoplasm

Elisa Izaurralde

Journal:

European Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

45

The PAM domain, a multi-protein complex-associated module with an all-alpha-helix fold

Francesca D Ciccarelli, Elisa Izaurralde, Peer Bork

Journal:

BMC Bioinformatics

Year:

2003

Language:

english

File:

PDF, 349 KB

english, 2003

46

The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex

Fromm, Simon A, Truffault, Vincent, Kamenz, Julia, Braun, Joerg E, Hoffmann, Niklas A, Izaurralde, Elisa, Sprangers, Remco

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.85 MB

english, 2011

47

TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus

Patric Grüter, Carlos Tabernero, Cayetano von Kobbe, Christel Schmitt, Claudio Saavedra, Angela Bachi, Matthias Wilm, Barbara K Felber, Elisa Izaurralde

Journal:

Year:

1998

Language:

english

File:

PDF, 289 KB

english, 1998

48

A Tiny Helper Lightens the Maternal Load

Detlef Weigel, Elisa Izaurralde

Journal:

Year:

2006

Language:

english

File:

PDF, 162 KB

english, 2006

49

Getting to the Root of miRNA-Mediated Gene Silencing

Ana Eulalio, Eric Huntzinger, Elisa Izaurralde

Journal:

Year:

2008

Language:

english

File:

PDF, 648 KB

english, 2008

50

SMG7 Acts as a Molecular Link between mRNA Surveillance and mRNA Decay

Leonie Unterholzner, Elisa Izaurralde

Journal:

Year:

2004

Language:

english

File:

PDF, 471 KB

english, 2004

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